Description

Product Name: Hydrolyzed Sodium Hyaluronate (Nanometer)
Molecular Weight Range: ≤1000 Da
Appearance: White or off-white fine powder with strong hygroscopicity, odorless
Functions: Deep skin hydration, collagen synthesis stimulation, anti-aging, elasticity improvement, wound repair enhancement
Molecular Formula: (C₁₄H₂₀NO₁₁Na)ₙ
CAS Number: 9067-32-7

Key Features and Benefits
1.Superior Moisturization & Deep Penetration：
With an average molecular weight ≤1000 Da, nmHA penetrates deeply into the dermal layer, locking in moisture and improving skin smoothness. Studies show that after 28 days of continuous use, skin hydration levels rise significantly, wrinkles visibly reduce, and more than 68% of users report noticeable improvement in overall skin condition.

2.Boosts Collagen Production：
nmHA supports the skin’s natural healing mechanism by stimulating fibroblast activity, promoting collagen synthesis, and restoring damaged skin tissue. This process helps recover elasticity and firmness, offering long-term anti-aging benefits.

3.Safe for Sensitive Skin：
Free from irritation and allergens, nmHA can be safely used in delicate formulations for sensitive or post-treatment skin. Its mild and natural characteristics ensure excellent tolerance across various cosmetic applications.

4.High Purity and Excellent Stability：
Our nmHA is carefully refined to maintain 97–99% sodium hyaluronate content and ≥46% glucuronic acid, surpassing international cosmetic standards. The solution remains clear and stable for 5 days without viscosity loss, ensuring reliable formulation performance.

5.Certified Quality and Eco-Conscious Manufacturing：
Produced under ISO9001, ISO14001, HACCP, and GMP certified systems, ensuring product traceability, environmental sustainability, and exceptional batch consistency.

Test Item	Requirement	Test Result
Appearance	White to off-white powder or granules	Compliant
IR Absorption	Matches reference spectrum	Compliant
Sodium Salt Reaction	Positive	Compliant
Glucuronic Acid (%)	≥45.0	47.07
Sodium Hyaluronate (%)	≥92.0	97.32
Average Molecular Weight	80–120% of labeled	821
Absorbance (5mg/ml, 280 nm)	≤0.25	0.045
Solution Transmittance (%)	≥99.0	100
Loss on Drying (%)	≤10.0	7.72
pH (5mg/ml)	5.0–8.5	6.08
Heavy Metals (Pb, mg/kg)	≤20	<20
Protein Content (%)	≤0.10	0.012
Total Microbial Count (CFU/g)	≤100	<10
Yeast & Mold (CFU/g)	≤50	<10
Staphylococcus aureus (CFU/g)	Not detectable	Not detected
Pseudomonas aeruginosa (CFU/g)	Not detectable	Not detected

Application Scope
1.Hydrolyzed Sodium Hyaluronate (Nanometer) is ideal for a wide range of industries and formulations:
2.Cosmetics & Personal Care: Facial serums, masks, lotions, creams, toners, sprays, and eye treatments
3.Sensitive Skin Products: Gentle moisturizers and post-procedure repair creams
4.Health & Nutrition: Functional foods, dietary supplements, and oral beauty products
5.Pharmaceuticals: Skin regeneration formulations, wound healing agents, and drug delivery enhancers

Why Choose Our Hydrolyzed Sodium Hyaluronate?
1.Measured Molecular Weight Accuracy: Each batch features a verified molecular weight, providing transparency for formulation control.
2.High Purity, No Discoloration: Pure white appearance with excellent solubility and no yellowish hue or residue.
3.Ultra-Low Impurities: Heavy metals — As <0.01, Pb <0.02; Endotoxin <0.07 EU/mg (far below pharmacopeia limits).
4.Stable pH: Maintained between 6.0–7.0 with minimal protein content (<0.05%), preventing irritation or sensitization.
5.Consistent Performance: Excellent stability across multiple batches; viscosity remains unchanged after 5 days.

How to Judge the Quality of Hydrolyzed Sodium Hyaluronate
1.Appearance: Should be pure white, fine, uniform, and free from dark impurities.
2.Transparency: When dissolved, the solution should be crystal-clear and colorless.
3.Particle Uniformity: Fine, even granules indicate excellent dehydration control.
4.Chemical Indicators: High glucuronic acid and low protein levels demonstrate superior quality.
5.Sterility & Microbial Control: Produced in aseptic environments with extremely low microbial counts.

Storage & Usage Guidelines
1.Use pure or distilled water for dissolving to maintain transparency.
2.Once dissolved, use immediately or add preservatives if storing for later use.
3.Avoid mixing with cationic surfactants or preservatives to prevent precipitation.
4.Store in a cool, dry environment (2–8°C) and seal tightly to prevent moisture absorption.

Application Industries
Cosmetics | Personal Care | Nutraceuticals | Functional Foods | Pharmaceuticals | Biotechnology | Health Products

Frequently Asked Questions (FAQ) — Hydrolyzed Sodium Hyaluronate (Nanometer / nmHA)

1. What is Hydrolyzed Sodium Hyaluronate (Nanometer)?

Hydrolyzed Sodium Hyaluronate, also known as Hyaluronic Acid Oligosaccharide (nmHA), is an ultra-low molecular weight form of hyaluronic acid (≤1000 Da). Its nano-sized molecules (approx. 6 nm) penetrate deeply into the skin, delivering moisture and nutrients directly to the dermal layer.

---

2. What are the main benefits of nmHA?

• Deep and fast hydration through enhanced skin penetration

• Stimulates collagen and elastin synthesis

• Reduces fine lines and wrinkles

• Improves skin elasticity, firmness, and radiance

• Strengthens the skin barrier for long-term hydration

---

3. How does nmHA differ from other forms of Sodium Hyaluronate?

• Oligomeric (≤10 kDa): Deeper hydration and rejuvenation

• Low Molecular (≤300 kDa): Deep hydration and anti-aging

• Medium Molecular (800–1500 kDa): Balanced moisture and viscosity

• High Molecular (≥1600 kDa): Surface film-forming and protection

• Nanometer (≤1000 Da): Fastest absorption, deepest penetration, strongest biological activity

nmHA works on the cellular level, promoting active skin repair beyond surface hydration.

---

4. What cosmetic applications is it suitable for?

Hydrolyzed Sodium Hyaluronate (Nanometer) is ideal for:

• High-end facial serums and essences

• Moisturizing and anti-aging creams

• Eye-area skincare

• Soothing and repair formulations

• Sheet masks and hydrating gels

• Advanced dermocosmetic and cosmeceutical lines

---

5. Can nmHA be used in nutraceutical or pharmaceutical products?

Yes. Its biocompatibility, safety, and small molecular size make it suitable for nutritional supplements (skin hydration, joint health) and pharmaceutical formulations (wound healing, topical repair).

---

6. What are the technical specifications?

• Molecular Weight: ≤1000 Da

• Particle Size: ~6 nm

• Structure: Hyaluronic acid oligosaccharides (di-, tetra-, and hexasaccharides)

• Purity: ≥95%

• Endotoxin: ≤0.5 EU/mg

• Appearance: White to off-white powder, highly soluble in water

---

7. What quality standards does it comply with?

Our nmHA is produced in ISO9001, HACCP, GMP, and ISO14001-certified facilities. Each batch is tested for purity, molecular integrity, microbial limits, and endotoxin to ensure consistency, safety, and performance.

---

8. Is Hydrolyzed Sodium Hyaluronate (Nanometer) safe for sensitive skin?

Yes. It is non-irritating, hypoallergenic, and biocompatible, making it safe for sensitive, dry, or aging skin. It also enhances tolerance in multi-active skincare formulas.

---

9. Is nmHA compatible with other cosmetic ingredients?

Yes. It has excellent compatibility with peptides, vitamins, niacinamide, ceramides, botanical extracts, and surfactants, maintaining stability and enhancing overall formula efficacy.

---

10. How should nmHA be stored?

Store in a cool, dry place (below 25°C), away from direct light and moisture. Keep the container tightly sealed. Shelf life: 24 months under recommended storage conditions.

---

11. Do you provide samples and technical documents?

Yes. We offer COA, TDS, MSDS, and formulation guidance. Free samples are available for product testing, R&D, and quality evaluation.