Cocrystal Technology

  • Curcumin Cocrystals ≥60% high-bioavailability Curcumin powder

    Curcumin Cocrystals ≥60% 60X Higher Absorption, Improved Solubility & Flowability

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    Curcumin Cocrystals Supplier ≥60% High-Bioavailability Curcumin Co-crystal

    Curcumin Cocrystals ≥60% 60X Higher Absorption, Improved Solubility & Flowability

    Curcumin Cocrystals are an advanced solid-state formulation of Curcumin developed using Co-crystal Technology to address the key application challenges of conventional Curcumin, particularly its extremely low water solubility and poor oral bioavailability.

    With ≥60% Curcumin content, this crystalline Curcumin powder is formed through the co-crystallization of Curcumin with an edible coformer. Through molecular-level non-covalent interactions and supramolecular self-assembly, the resulting Curcumin Co-crystal Structure is designed to improve physicochemical properties while maintaining Curcumin as the active ingredient.

    Compared with conventional Curcumin ingredients, Curcumin Cocrystals offer improved dissolution and absorption performance, enhanced powder flowability, a cleaner formulation profile, and better processing characteristics. Human clinical research has reported up to 60× higher absorption under the tested conditions, highlighting the potential of Co-crystal Technology for developing advanced Curcumin formulations.

    For global dietary supplement manufacturers, nutraceutical brands, and functional food manufacturers, Curcumin Cocrystals provide a differentiated approach to developing high-bioavailability Curcumin products without relying on piperine, added emulsifiers, or additional dispersing systems in the formulation, subject to the product’s specifications and intended application.

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    • Hydroxytyrosol Cocrystals ≥53% crystalline powder

      Hydroxytyrosol Cocrystals ≥53% Low Hygroscopicity, High Stability & Excellent Flowability

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      Hydroxytyrosol Cocrystals Supplier ≥53% Stable Hydroxytyrosol Co-crystal

      Hydroxytyrosol Cocrystals ≥53% Low Hygroscopicity, High Stability & Excellent Flowability

      Hydroxytyrosol Cocrystals are an advanced crystalline form of Hydroxytyrosol developed using Co-crystal Technology to overcome the poor physical stability and processing limitations of conventional Hydroxytyrosol.

      Hydroxytyrosol is an important bioactive component of olive-derived polyphenols, but conventional Hydroxytyrosol has a major formulation challenge: it has a low melting point and is highly hygroscopic. After absorbing moisture, it can become sticky and syrup-like, making conventional Hydroxytyrosol difficult to handle, accurately dose and process into solid dosage forms.

      Our Hydroxytyrosol Cocrystals contain ≥53% active Hydroxytyrosol and transform the conventional sticky or oily material into a free-flowing crystalline powder with low hygroscopicity and excellent physical and chemical stability.

      Through Co-crystal Technology, Hydroxytyrosol is combined with an edible coformer at the molecular level to form a new crystalline structure. The resulting Hydroxytyrosol Cocrystals provide a more practical ingredient format for softgels, hard capsules, tablets, gummies and powder formulations, supporting the formulation needs of dietary supplement manufacturers, nutraceutical brands and functional ingredient developers.

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      • Lutein Cocrystals ≥60% high-bioavailability crystalline powder

        Lutein Cocrystals ≥60% 3.4X Higher Absorption, Enhanced Stability & Solubility

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        Lutein Cocrystals Supplier ≥60% High-Bioavailability Lutein Co-crystal

        Lutein Cocrystals ≥60% 3.4X Higher Absorption, Enhanced Stability & Solubility

        Lutein Cocrystals are an advanced solid-state form of Lutein developed using Co-crystal Technology to address the key formulation challenges of conventional Lutein ingredients, including poor stability, extremely low solubility, and limited bioavailability.

        With ≥60% active Lutein, this crystalline powder is produced by co-crystallizing natural Lutein with an edible coformer through controlled molecular interactions. The resulting Lutein Co-crystal Structure is designed to improve the physical and chemical properties of Lutein while maintaining Lutein as the active ingredient.

        Compared with conventional Lutein raw materials, Lutein Cocrystals offer enhanced stability, approximately 5× higher solubility, and improved absorption performance. Human clinical research supplied for this product reports 3.4× higher absorption compared with conventional Lutein crystals.

        Unlike microencapsulated Lutein powder, Lutein Cocrystals are not based on microencapsulation technology. Instead, the active ingredient itself is engineered into a new crystalline form, providing excellent flowability, high active content, and a simplified formulation without the need for added emulsifiers or dispersants in the co-crystal ingredient, subject to the product’s specifications.

        Designed for dietary supplement manufacturers, nutraceutical brands, and functional food developers, Lutein Cocrystals offer an alternative to conventional Lutein ingredients for developing innovative formulations in tablets, capsules, powders, and other nutritional supplement products.

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        • Oregano Essential Oil Cocrystals with Carvacrol and Thymol crystalline powder

          Oregano Essential Oil Cocrystals Carvacrol & Thymol Feed Additive for Animal Nutrition

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          Oregano Essential Oil Cocrystals Supplier Carvacrol & Thymol Feed Additivel

          Oregano Essential Oil Cocrystals Carvacrol & Thymol Feed Additive for Animal Nutrition

          Oregano Essential Oil Cocrystals are an advanced solid-state botanical feed additive developed from the key active components of oregano essential oil, primarily Carvacrol and Thymol, using innovative Co-crystal Technology. Designed for the animal feed and animal nutrition industries, this ingredient transforms volatile essential oil components into a convenient crystalline powder for modern feed formulations.

          Natural Carvacrol and Thymol are widely studied active compounds of oregano essential oil. However, their low melting point, volatility, oxidation sensitivity, and processing limitations can affect stability during feed manufacturing and storage. Oregano Essential Oil Cocrystals are designed to address these challenges by converting the volatile oil components into a crystalline powder with a higher melting point and lower volatility, supporting improved handling and formulation convenience.

          The product is available in two standardized specifications: Carvacrol ≥7.5% + Thymol ≥7.5% and Carvacrol ≥12.5% + Thymol ≥12.5%. These standardized Carvacrol and Thymol concentrations allow animal feed manufacturers, feed additive suppliers, and animal nutrition companies to select a suitable specification according to their formulation requirements and target animal species.

          With its crystalline powder format, improved handling characteristics, and potential stability advantages over highly volatile essential oil components, Oregano Essential Oil Cocrystals are designed for a range of animal nutrition applications, including swine feed, poultry feed, and aquaculture feed. For global B2B buyers seeking oregano essential oil feed additives, Carvacrol and Thymol powder, or innovative botanical feed ingredients, this product offers a differentiated feed additive solution for modern animal nutrition formulations.

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          • Rutin Cocrystals ≥60% high-solubility Rutin crystalline powder

            Rutin Cocrystals ≥60% 40X Higher Solubility, 5× Higher Absorption

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            Rutin Cocrystals Supplier ≥60% High-Solubility Rutin Co-crystal

            Rutin Cocrystals ≥60% 40X Higher Solubility, 5× Higher Absorption

            Rutin Cocrystals are an advanced solid-state form of Rutin developed using Co-crystal Technology to overcome the poor water solubility and limited absorption of conventional Rutin. With an active Rutin content of ≥60%, the product is designed for formulations requiring higher solubility, faster dissolution and improved bioavailability.

            Compared with conventional Rutin, Rutin Cocrystals can achieve up to 40× higher solubility, with solubility reaching up to 2 mg/mL, while supplied product data reports approximately 5× higher absorption. The improved dissolution profile provides greater formulation flexibility for modern nutritional ingredients and functional ingredient applications.

            Unlike conventional Rutin powder or simple physical mixtures, Rutin Cocrystals are formed through molecular-level interactions between Rutin and an edible coformer, producing a defined crystalline structure. The resulting spherical crystalline powder offers high water solubility, good flowability and improved formulation performance.

            With its combination of high active content and advanced solid-state engineering, Rutin Cocrystals are suitable for dietary supplements, functional foods, cosmetics and other advanced formulations, including capsules, tablets, gummies and powder products.

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            • Silybin Cocrystals ≥60% crystalline powder

              Silybin Cocrystals ≥60% 16X Higher Absorption, 100X Solubility

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              Silybin Cocrystals Supplier ≥60% High-Bioavailability Silybin Co-crystal

              Silybin Cocrystals ≥60% 16X Higher Absorption, 100X Solubility

              Silybin Cocrystals are an advanced crystalline form of Silybin developed using Co-crystal Technology to address the key formulation limitations of conventional Silybin ingredients, particularly their poor water solubility and low oral bioavailability.

              With ≥60% Silybin content, this advanced Silybin ingredient is designed to provide improved physicochemical properties compared with conventional Silybin materials. According to the available product data, Silybin Cocrystals offer up to 100× higher solubility and 16× higher absorption, creating greater formulation flexibility and the potential to achieve targeted formulation performance at a lower dosage, depending on the application and supporting evidence.

              Unlike conventional Silybin powder or microencapsulated Silybin products, Silybin Cocrystals use solid-state engineering to form a new crystalline structure through molecular-level interactions between Silybin and an edible coformer. This distinctive co-crystal formulation offers an alternative for dietary supplement manufacturers seeking high-solubility, high-bioavailability Silybin ingredients for advanced nutritional formulations.

              Silybin Cocrystals are suitable for formulation development involving hard capsules, softgels, tablets, gummies, and powders. They can serve as an advanced Silybin raw material for dietary supplements, functional foods, and other nutritional applications, offering ingredient developers greater flexibility in designing differentiated products.

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              • Ubiquinol Co-crystal CoQ10 83% powder with enhanced stability and bioavailability

                Ubiquinol Cocrystal CoQ10 ≥83% Enhanced Stability, Solubility & Bioavailability

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                Ubiquinol Cocrystal CoQ10 Supplier ≥83% CoQ10 with Enhanced Stability

                Ubiquinol Cocrystal CoQ10 ≥83% Enhanced Stability, Solubility & Bioavailability

                Co-crystal Ubiquinol CoQ10 is an advanced co-crystal formulation designed to address the key formulation challenges of conventional reduced Coenzyme Q10 (Ubiquinol), particularly its poor stability and low water solubility.

                Using Co-crystal Technology, Ubiquinol is combined with an edible coformer through non-covalent molecular interactions to form a defined crystalline structure. This supramolecular organization can improve important physicochemical properties while maintaining the identity and functional activity of the active ingredient.

                With ≥83% active content, Co-crystal Ubiquinol CoQ10 is designed to provide improved stability, solubility, and dissolution performance, as well as potentially enhanced oral absorption, compared with conventional Ubiquinol. The technology also offers greater formulation flexibility for finished products, including softgels, hard capsules, tablets, gummies, and powders.

                For dietary supplement manufacturers, nutraceutical brands, and ingredient distributors seeking a more stable and formulation-friendly Ubiquinol ingredient, Co-crystal Ubiquinol CoQ10 offers a differentiated technical solution beyond conventional CoQ10 powders and standard Ubiquinol products

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                • Urolithin A Cocrystals ≥55% crystalline powder

                  Urolithin A Cocrystals ≥55% 18X Higher Solubility, Enhanced Tissue Exposure

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                  Urolithin A Cocrystals Supplier ≥55% Urolithin A Co-crystal

                  Urolithin A Cocrystals ≥55% 18X Higher Solubility, Enhanced Tissue Exposure

                  Urolithin A Cocrystals are an advanced crystalline form of Urolithin A (UA) developed using Hydrogen-Bond Co-crystal Technology with L-Carnitine as the coformer.

                  Urolithin A (UA) has attracted significant interest as a next-generation nutritional ingredient, but conventional Urolithin A has important formulation limitations, including extremely low water solubility and low oral bioavailability. These properties can restrict dissolution, systemic exposure and the practical development of high-performance nutritional formulations.

                  Our Urolithin A Cocrystals contain ≥55% active Urolithin A and are designed to address these limitations at the solid-state level. The product data demonstrates 18× higher solubility, together with substantially increased concentrations in blood, muscle and brain tissue.

                  Unlike a simple physical mixture of Urolithin A and L-Carnitine, the two components are combined through molecular-level hydrogen bonding to form a defined Urolithin A Co-crystal structure.

                  This provides formulators with a differentiated Urolithin A ingredient for advanced dietary supplements, functional nutrition products and next-generation active-ingredient formulations.

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                  • Vitamin E Cocrystals ≥80% natural d-alpha-tocopherol crystalline powder

                    Vitamin E Cocrystals ≥80% Natural d-Alpha-Tocopherol, High Bioavailability

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                    Vitamin E Cocrystals Supplier ≥80% Natural d-Alpha-Tocopherol Co-crystal

                    Vitamin E Cocrystals ≥80% Natural d-Alpha-Tocopherol, High Bioavailability

                    Vitamin E Cocrystals are an advanced natural Vitamin E ingredient developed from d-alpha-tocopherol (d-α-tocopherol) through innovative Co-crystal Technology. With a natural Vitamin E content of ≥80%, this ingredient transforms naturally oily Vitamin E into a free-flowing crystalline powder, offering improved handling and processing convenience for dietary supplements, nutraceuticals, and functional food formulations.

                    Unlike conventional powdered Vitamin E ingredients that rely on chemical derivatization or microencapsulation technology, Vitamin E Cocrystals are developed without chemical modification of the Vitamin E molecule and without conventional microencapsulation. This approach helps retain the natural identity of d-alpha-tocopherol while providing a practical solid powder format for modern formulation development.

                    The resulting crystalline Vitamin E powder offers excellent flowability, good tablet compression performance, and suitability for solid dosage applications. According to the supplied product data, it provides a 30–56% improvement in absorption compared with the relevant conventional Vitamin E form. Its high active content may also help reduce finished-product tablet weight by approximately 2–4× in suitable formulations, supporting more compact product designs.

                    For global ingredient buyers seeking natural Vitamin E powder, high-content d-alpha-tocopherol, and innovative Vitamin E ingredients for tablets and dietary supplements, Vitamin E Cocrystals offer a differentiated alternative to conventional Vitamin E esters and microencapsulated Vitamin E powders. This advanced ingredient is designed for nutraceutical manufacturers, dietary supplement brands, contract manufacturers, and B2B ingredient distributors looking for improved powder handling, efficient tablet formulation, and next-generation Vitamin E delivery solutions.

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