High Purity Cationic Sodium Hyaluronate for Long-Lasting Hydration
High Purity Cationic Sodium Hyaluronate for Long-Lasting Hydration
Cationic Sodium Hyaluronate Hair & Skin Moisturizer
Cationic Sodium Hyaluronate is an advanced derivative of conventional sodium hyaluronate (HA), specifically engineered to maximize moisturizing performance on skin and hair. Traditional HA carries negative charges due to carboxyl groups. Since human skin and hair surfaces are also negatively charged, standard HA binds poorly and is easily rinsed off, reducing its hydration efficiency.
Cationic modification introduces positive charges, allowing HA to electrostatically adhere to hair and skin surfaces. This results in improved water retention, long-lasting moisturizing effects, and enhanced skin and hair conditioning without compromising HA’s natural hydrating properties.
Description
Product Name: Cationic Sodium Hyaluronate
Molecular Weight Range: Customizable (Low, Medium, High Molecular Weight Options)
Appearance: White to off-white fine powder, dissolves into clear, transparent solution, free from visible impurities
Functions: High-adhesion moisturizing agent, film-forming, hair & scalp conditioning, skin hydration
Molecular Formula: (C₁₄H₂₁NO₁₁)ₙ (cationically modified)
Molecular Weight: Varies by series

Key Product Features:
1.High Adhesion & Retention: Ensures scalp and hair remain nourished and moisturized. Forms a protective film, preventing irritation while enhancing hydration.
2.Silky & Non-Sticky: Optimized viscosity delivers smooth skin feel and hair texture without greasiness. Reduces surfactant-induced irritation on the scalp.
3.Wash-Resistant & High Affinity: Maintains hydration on hair and scalp even after washing, alleviating dryness, itchiness, and flaking caused by insufficient moisture.
4.Safe & Stable: Produced in ISO9001, HACCP, GMP certified facilities, under ISO14001 environmental management system. Low protein, minimal endotoxin, and trace heavy metals guarantee safety.
5.Excellent Compatibility: Fully compatible with glycerin, surfactants, peptides, and functional actives, suitable for diverse cosmetic formulations.
6.Superior Stability: Batch-to-batch consistency confirmed with minimal viscosity change over 3–5 days, ensuring stable slow-release hydration.
| Parameter | Specification |
| Glucuronic Acid (dry basis) | 37.0–46.0% |
| pH | 5.0–7.5 |
| Absorbance (A280nm) | ≤0.25 |
| Transmittance (T550nm) | ≥99.0% |
| Loss on Drying | ≤10% |
| Residue on Ignition | ≤15% |
| Kinematic Viscosity | 2–10 mm²/s |
| Cationic Degree | 0.15–0.60 |
| Protein | ≤0.1% |
| Heavy Metals (as Pb) | ≤20 mg/kg |
| Total Plate Count | ≤100 CFU/g |
| Yeast & Mold | ≤50 CFU/g |
| Staphylococcus aureus | Not detectable |
| Pseudomonas aeruginosa | Not detectable |
Applications:
1.Haircare: Shampoos, conditioners, hair masks, scalp serums
2.Skincare: Moisturizers, facial masks, serums, creams, lotions
3.Cleansing Products: Facial cleansers, body washes, cleansing gels
4.Other Industries: Functional foods, supplements, nutraceuticals, pharmaceutical formulations
Why Choose Our Cationic HA?
1.High content: Glucuronic acid ≥46%, HA concentration 97–99%, exceeding industry standards
2.Accurate molecular weight labeling for precise formulation selection
3.pH 6–7, protein ≤0.05%, avoiding skin sensitivity
4.Heavy metals: Pb <0.02 mg/kg, As <0.01 mg/kg
5.Endotoxin ≤0.07 EU/mg, far below pharmacopoeia limits
6.Low molecular weight series: pure white, fully transparent solution, no yellowing
Usage Instructions:
1.Dissolve in pure or distilled water for optimal clarity.
2.Use freshly prepared solutions or store with preservatives to prevent microbial growth.
3.Avoid combining with cationic surfactants or preservatives to prevent precipitation.
4.Store in sealed, dry, low-temperature conditions (2–8°C) to prevent moisture absorption.
| Cationic HA vs Acetylated HA – Comparison Table | ||
| Feature | Cationic Sodium Hyaluronate (cHA) | Acetylated Sodium Hyaluronate (AcHA) |
| Charge | Positive (cationic) | Neutral/lipophilic (acetyl-modified) |
| Skin/Hair Affinity | Strong adhesion to negatively charged skin and hair; resistant to rinsing | High skin penetration and adhesion due to lipophilic acetyl groups |
| Primary Function | Hair & scalp hydration, film-forming protection | Skin moisturizing, barrier repair, elasticity enhancement |
| Water Retention | High, mainly on hair & skin surface | Double hydration in stratum corneum, long-lasting skin hydration |
| Film Formation | Forms protective layer on hair & scalp | Forms dense hydration layer on skin; improves barrier function |
| Suitable Applications | Shampoos, conditioners, hair masks, body wash | Serums, creams, lotions, facial masks, anti-aging skincare |
| Bioactivity | Moderate | High, enhances cell proliferation & barrier repair |
| Formulation Compatibility | Avoid cationic surfactants or preservatives | Compatible with surfactants, peptides, actives |
| Key Advantages | Resistant to rinsing, silky hair feel | Deep skin hydration, repair dry/damaged skin, improves elasticity |
Quality Evaluation Criteria:
1.Powder should appear pure white, fine, and free of black specks
2.Low microbial count as per specifications
3.Uniform particle size without oversized granules
4.Solution should be clear and transparent
5.Glucuronic acid content indicates HA concentration
6.Low protein content ensures low allergenicity
Why Choose Us?
1.We are a leading global supplier of premium cationic sodium hyaluronate, providing:
2.Stable, high-purity, and safe HA for cosmetic, haircare, personal care, functional food, and pharmaceutical industries
3.Fully certified production (ISO9001, HACCP, GMP, ISO14001)
4.Batch-to-batch consistency, high performance, and technical formulation support
Cationic Sodium Hyaluronate – Frequently Asked Questions (FAQ)
1. What is Cationic Sodium Hyaluronate?
Cationic Sodium Hyaluronate is a positively charged derivative of traditional sodium hyaluronate (HA). It is specially modified to improve adhesion to negatively charged surfaces such as skin and hair, providing longer-lasting moisturization and conditioning effects.
2. How does Cationic Sodium Hyaluronate differ from regular Sodium Hyaluronate?
Conventional sodium hyaluronate carries negative charges and does not bind well to skin or hair, which are also negatively charged.
Cationic Sodium Hyaluronate, however, contains positively charged functional groups that enable electrostatic attraction, improving its deposition, retention, and overall moisturizing performance.
3. What are the main benefits of using Cationic Sodium Hyaluronate in cosmetics?
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Long-lasting hydration and moisture retention
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Enhanced skin and hair adhesion
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Improved smoothness and softness
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Stronger barrier protection
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Reduced wash-off during cleansing or rinsing
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Ideal for long-lasting moisturizers, conditioners, and hair treatments
4. Is Cationic Sodium Hyaluronate safe for skin and hair?
Yes. It is derived from natural sodium hyaluronate and modified through a mild cationic process that maintains biocompatibility. It is non-irritating, non-toxic, and suitable for sensitive skin and scalp applications.
5. What types of formulations is it suitable for?
Cationic Sodium Hyaluronate can be widely used in:
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Facial and body moisturizers
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Serums and essences
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Hair conditioners and masks
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Shampoos and leave-in treatments
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Makeup bases and skin primers
6. What concentration is recommended in formulations?
The recommended dosage is typically 0.05–1.0%, depending on product type and desired sensory effect. For hair care applications, slightly higher levels may be used to improve conditioning performance.
7. How does it improve hair care products?
The cationic charge allows it to bond firmly with the hair cuticle, forming a hydrating, protective film that enhances smoothness, shine, and manageability while reducing frizz and breakage.
8. Does it affect the viscosity or stability of cosmetic formulations?
Cationic Sodium Hyaluronate has minimal impact on viscosity and is compatible with most cosmetic ingredients. It can be easily incorporated into aqueous systems and emulsions under normal formulation conditions.
9. Is it compatible with anionic surfactants or other ingredients?
Yes. Despite its cationic nature, it shows good compatibility with common anionic surfactants used in shampoos and cleansers, making it a versatile moisturizing and conditioning additive.
10. What is the source of raw material?
The base material—sodium hyaluronate—is typically derived from natural fermentation of non-animal sources, ensuring sustainability, purity, and safety for global cosmetic applications.
11. What are the storage and stability recommendations?
Store in a cool, dry place away from direct sunlight and moisture. When properly stored, the product maintains stability for up to 24 months in its original, unopened packaging.





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