Low Molecular Weight Sodium Hyaluronate Food Grade High Purity
Low Molecular Weight Sodium Hyaluronate Food Grade High Purity
Food Grade HA Sodium Hyaluronate 100-200kDa
Low Molecular Weight Sodium Hyaluronate (HA-F) is a food-grade sodium hyaluronate with a molecular weight range of 100kDa–200kDa. As a natural component of human dermal tissue, hyaluronic acid (HA) is one of the most abundant acidic polysaccharides in the human body. It consists of repeating disaccharide units of N-acetylglucosamine and D-glucuronic acid, forming linear polysaccharides capable of binding water up to 1000 times their weight.
Unlike topical HA, which primarily affects the skin surface, oral consumption of HA replenishes the body’s internal stores, acting as a “second-generation nutrient.” It is absorbed through the intestinal and gastric mucosa into the bloodstream, distributed throughout organs and tissues, and forms a unique three-dimensional structure that supports collagen and elastin synthesis in the dermis. Oral HA enhances hydration, delays aging, supports joint health, and contributes to cardiovascular and brain health.
Applications include: otolaryngology, oncology, dentistry, wound healing, dietary supplements, ophthalmology, urology, skincare, orthopedics, soft tissue filling, and respiratory medicine.
Description

Product Overview:
Product Name: Low Molecular Weight Sodium Hyaluronate(HA-F)
Molecular Weight: 100–200 kDa
Appearance: White, fine, crystalline powder
High HA content ≥96%
Glucuronic Acid Content: ≥46%
pH Value: 6–7
Protein Content: <0.05%
Heavy Metals: As <0.01ppm, Pb <0.02ppm
Endotoxin Level: 0.07 EU/mg (far below pharmacopoeia limits)
Shelf Life: 24 months under dry, cool storage
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Item | Standard |
| Appearance | White Powder | |
| PH | 6.0-8.0 | |
| Transparency | ≥99.0% | |
| Loss Ondrying | ≤8.0% | |
| Bulk Density | Practical Value | |
| Molecular Weight | Practical Value | |
| Bacterial Endotoxin | <0.5EU/mg | |
| Residue On Ignition | ≤13.0% | |
| Heavy Metals | ≤20ppm | |
| Arsenic | ≤20ppm | |
| Glucuronic Acid | ≥44.0% | |
| HA | ≥96.0% | |
| Bacterial Counts | ≤100cfu/g | |
| Mold & Yeast | <10cfu/g | |
| E.Coli | Negative | |
| Staphylococcus Aureus | Negative | |
| Salmonella | Negative |
Key benefits of oral HA:
1.Skin: Deep nourishment, elasticity improvement, wrinkle reduction.
2.Eyes: Maintains ocular moisture, alleviates dryness and irritation.
3.Brain: Supports osmotic balance and neural tissue nutrition.
4.Joints: Natural shock absorber, relieves inflammation and pain, increases flexibility.
5.Gastrointestinal: Protects gastric mucosa and improves gut function.
6.Healing: Accelerates wound recovery.
7.Antimicrobial: Acts as a natural barrier against bacteria and viruses.
8.Immunity: Supports normal bodily functions and enhances energy levels.
9.Cardiovascular & Brain: Helps prevent atherosclerosis, arrhythmia, and brain atrophy.
HA is widely used in beverages, dairy products, functional foods, capsules, tablets, and liquid formulations, often in combination with collagen, vitamins, glucosamine, or chondroitin sulfate.
| Food Grade Sodium Hyaluronate | |||
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| ltem | Product Code | Molecular Weight | Function |
| Sodium Hyaleronate | HA-F | 100kDa~200kDa | anti-aging,reduce inflam-mation,lubricate joints,flooding-pain and sooth wrinkle |
| 200kDa~400kDa | |||
| 400kDa~600kDa | |||
Certifications & Quality Assurance:
Kosher & Halal Certified
ISO 9001 / GMP Compliant
Non-GMO, low heavy metals, low endotoxin, high stability
Why Choose Us:
1.Stable, high-purity HA with minimal batch variation
2.Precise molecular weight labeling for easy selection
3.Excellent solubility, clear appearance without yellowing
4.Comprehensive global supply and OEM/ODM support
5.Advanced production under sterile conditions ensuring safety and consistency
Our Product Features:
1.Excellent hydrolysis stability, maintaining viscosity over 3–5 days.
2.High HA content (Purity: ≥96%) with glucuronic acid ≥46%, exceeding national standards.
3.Transparent and accurate molecular weight labeling for efficiency in selection.
4.Stable pH (6–7) and very low protein (<0.05%) to prevent allergenic reactions.
5.Low heavy metal content and endotoxin levels well below regulatory limits.
6.Pure white powder, dissolves to clear transparent solution; superior to yellowing products from other suppliers.
How to Judge HA Quality:
1.Appearance: pure white, fine, no black particles.
2.Produced under sterile conditions; low microbial count.
3.Particle size: uniform and not excessively large.
4.Solution transparency: clear and colorless, indicating high purity.
5.Glucuronic acid content: indicator of HA content.
6.Protein control: low protein reduces allergenic risks.
Storage & Handling:
1.Keep in a cool, dry, sealed, and dark environment.
2.Avoid cationic surfactants to prevent precipitation.
3.Dissolve in sterilized distilled or deionized water, temperature ≤60℃.
4.After opening, residual powder should be sealed in sterile conditions.
5.Use preservatives if not consumed immediately after dissolution.
FAQ: Low Molecular Weight Sodium Hyaluronate (HA-F)
1. What is Low Molecular Weight Sodium Hyaluronate (HA-F)?
Answer: HA-F is a food-grade sodium hyaluronate with a molecular weight of 100–200 kDa. It is a naturally occurring polysaccharide in the human body that binds water efficiently, supporting skin, joint, and tissue health.
2. How does HA-F differ from regular hyaluronic acid?
Answer: Unlike high molecular weight HA, HA-F has a smaller molecular size, making it suitable for oral absorption. While topical HA mainly hydrates the skin surface, HA-F replenishes the body’s internal HA stores for systemic benefits.
3. How is HA-F absorbed and utilized by the body?
Answer: HA-F is absorbed through the intestinal and gastric mucosa into the bloodstream. It is distributed to organs and tissues, forming a three-dimensional structure that promotes collagen and elastin synthesis in the dermis.
4. What are the main health benefits of HA-F?
Answer: Oral HA-F supports:
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Skin hydration and elasticity
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Anti-aging effects
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Joint health
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Cardiovascular and brain health
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Wound healing and tissue repair
5. What are the main applications of HA-F?
Answer: HA-F is used in:
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Dietary supplements and functional foods
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Skincare and cosmetics
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Ophthalmology and urology
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Orthopedics and soft tissue repair
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Wound healing and dentistry
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Otolaryngology, oncology, and respiratory medicine
6. Is HA-F safe for daily consumption?
Answer: Yes. HA-F is food-grade, non-toxic, and generally recognized as safe for daily oral consumption when used according to recommended dosages.
7. What makes low molecular weight HA more effective orally?
Answer: Its smaller molecular size allows it to pass through the digestive tract more easily and enter the bloodstream, where it supports hydration, tissue regeneration, and collagen synthesis.
8. How should HA-F be stored?
Answer: Store in a cool, dry place, away from direct sunlight. Keep the container tightly closed to maintain stability and prevent moisture absorption.
9. Can HA-F be combined with other nutrients or supplements?
Answer: Yes. HA-F is compatible with vitamins, minerals, antioxidants, and other functional ingredients commonly used in nutraceuticals and dietary supplements.
10. Are there any side effects or contraindications?
Answer: HA-F is generally well tolerated. Individuals with specific allergies or medical conditions should consult a healthcare professional before use.







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