Description

Diosgenin Extract

Diosgenin, a bioactive steroidal sapogenin derived from Dioscorea roots, serves as a critical precursor for synthesizing steroid hormones (e.g., progesterone, cortisone) and a natural phytoestrogen for women’s health. Our USP-grade extract (≥98% purity) is manufactured using solvent-free supercritical CO2 extraction, ensuring compliance with global pharmacopeial standards. Ideal for hormone replacement therapies (HRT), osteoporosis supplements, and API production, we offer scalable bulk sourcing and formulation flexibility.

Source: Ethically cultivated Dioscorea villosa or Dioscorea zingiberensis.
Purity: ≥98% (HPLC/USP/EP verified, melting point 205-208°C).

Applications:
Menopause Supplements: Phytoestrogen for hot flash relief and hormonal balance.
Osteoporosis Formulas: Enhances bone density via osteoclast inhibition.
Steroid API Synthesis: Key precursor for corticosteroids, contraceptives, and anti-inflammatory drugs.

Certifications: USP/EP compliance, GMP, ISO 9001, Kosher, Halal, Non-GMO.
Packaging: 1kg vacuum-sealed bags, 5kg/25kg drums (desiccant included); cold-chain shipping for stability.

Key Features & Benefits:
1.Dual-Action Efficacy:
1.1Phytoestrogen Activity: Binds to estrogen receptors to alleviate menopausal symptoms without synthetic HRT risks.
1.2Bone Health Support: Inhibits RANKL-induced osteoclastogenesis, reducing postmenopausal bone loss.
2.Pharmaceutical-Grade Quality:
USP/EP-compliant purity (≥98%) with batch-specific COA, heavy metal, and residual solvent testing.
3.Steroid Synthesis Versatility:
Chemically modified into intermediates like pregnenolone and dehydroepiandrosterone (DHEA) for API production.
4.Sustainable Extraction:
Supercritical CO2 and chromatography purification ensure minimal environmental impact.
5.Stability & Bioavailability:
Encapsulated formats available for enhanced solubility and shelf life in supplement formulations.
6.Regulatory Readiness:
Supports FDA DMF filings and EU herbal monographs for streamlined market entry.

Recommended Uses:
1.Hormone Replacement Therapy (HRT): Capsules or transdermal patches for menopausal symptom management.
2.Bone Density Formulas: Blends with calcium, vitamin D3, and collagen for osteoporosis prevention.
3.Steroid API Manufacturing: Raw material for cortisone, testosterone, and contraceptive synthesis.
4.Cosmeceuticals: Anti-aging creams leveraging phytoestrogen-driven collagen synthesis.

Customization & OEM Services:
1.Purity & Format: Adjust purity (95%-99%), particle size (micronized/nano), or solubility (water-dispersible emulsions).
2.Blending Expertise: Pre-formulated complexes with black cohosh, isoflavones, or hyaluronic acid.
3.Private Labeling: Custom branding, packaging (blister packs, bulk drums), and regulatory documentation (COA, MSDS, stability reports).
4.Technical Support: Bioavailability studies, dissolution testing, and API synthesis pathway optimization.
5.Supply Chain Assurance: Auditable traceability from farm to API, with cold-chain logistics for heat-sensitive batches.