Fisetin 98% HPLC Neuroprotective API for Clean-Label Formulas
Fisetin 98% HPLC Neuroprotective API for Clean-Label Formulas
Fisetin 98% Neuroprotective API Powder
Our Fisetin Powder is a premium-grade, neuroprotective flavonoid ingredient with HPLC-verified purity of 98%, standardized by external reference with actual tested content at 91% (external standard ≥80%). This active pharmaceutical ingredient (API) is known for its antioxidant, anti-inflammatory, and cognitive-enhancing properties. Certified under cGMP, HACCP, Halal, Kosher, IAF, and SGS third-party testing standards, our Fisetin is suitable for advanced formulations in functional foods, nutraceuticals, skincare, and dietary supplements. With comprehensive OEM/ODM customization services and global regulatory compliance, we are your ideal supplier for bulk Fisetin tailored to international industrial needs.
Description
Fisetin 98%
Fisetin (CAS No: 528-48-3) is a plant-derived flavonoid recognized for its potent neuroprotective and antioxidant properties. Extracted from botanical sources and purified through advanced technology, our Fisetin Powder is standardized to 98% purity via the HPLC method, with an actual external standard content of 91% (measured against an 80% external benchmark).
Our production strictly adheres to cGMP, HACCP, and global quality control protocols. The resulting powder is a clean-label, pharmaceutical-grade ingredient, ideal for mental clarity supplements, anti-aging skincare, and cognitive support formulas. We offer flexible bulk supply, private labeling, and formulation customization to suit international clients in the USA, EU, Middle East, and Asia-Pacific regions.

Fisetin Production Flowchart:
1.Botanical Sourcing
▪ High-quality plant materials rich in Fisetin are ethically sourced from approved botanical origins.
2.Raw Material Testing
▪ Incoming herbs undergo identity verification, microbial testing, and pesticide screening to ensure safety and compliance.
3.Extraction & Isolation
▪ Advanced extraction techniques are applied to isolate Fisetin. Solvent recovery and purification steps follow strict environmental and safety standards.
4.Purification & HPLC Standardization
▪ Fisetin is purified and standardized to ≥98% using HPLC analysis, with actual external benchmark results showing 91% content based on an 80% standard.
5.Drying & Milling
▪ The purified compound is vacuum-dried and finely milled into a consistent, pharmaceutical-grade powder.
6.Quality Control & Certification
▪ Final batches undergo rigorous lab testing for purity, heavy metals, microbial limits, residual solvents, and potency validation.
7.Packaging
▪ Packed in food/pharma-grade moisture-proof bags or drums, with nitrogen flush or vacuum seal options for global shipping.

🔹 Certifications
✅ cGMP (Current Good Manufacturing Practices)
✅ HACCP (Hazard Analysis Critical Control Point)
✅ SGS Third-Party Verified
✅ IAF Accredited
✅ Halal Certified
✅ Kosher Certified
✅ Clean Label (No Preservatives, No Additives)
✅ Heavy Metals, Pesticides, Residual Solvents Tested
🔹 Product Highlights
🧠 Neuroprotective Properties – Fisetin has shown potential in supporting brain health and protecting neurons from oxidative stress.
🌿 HPLC-Verified Purity – 98% assay with 91% external standard actual content ensures pharmaceutical-grade quality.
🔬 Scientifically Researched – Recognized in academic and clinical research for anti-aging, cognition, and inflammation modulation.
🌍 Global Compliance – Produced under international quality systems for broad-market registration and import/export.
📦 Bulk & Flexible Supply – Available in commercial volumes with customization options for concentration and particle size.
🌱 Clean & Natural – Derived from botanical sources with no artificial substances or fillers.
🔹 Product Benefits
✅ Cognitive Enhancement – Supports mental clarity, memory retention, and neuroplasticity.
✅ Anti-Aging Applications – May slow cellular senescence and reduce oxidative damage in aging cells.
✅ Anti-Inflammatory Support – Modulates inflammatory pathways, making it suitable for wellness and recovery formulations.
✅ Skin Health & Beauty – Antioxidant activity supports anti-aging skincare products such as serums and creams.
✅ Cellular Health & Detox – Promotes detoxification and cellular protection mechanisms.
✅ Nootropic Ingredient – An emerging compound in brain-health and nootropic supplements.

🔹 Application Areas
🧪 Dietary Supplements – Ideal for use in capsules, tablets, sachets, and powders targeting cognitive, aging, and wellness markets.
🧴 Skincare & Cosmetics – Suitable for anti-aging creams, serums, and dermaceuticals targeting oxidative skin stress.
🍵 Functional Foods & Beverages – Can be incorporated into smoothies, tonics, energy shots, or functional drinks.
💊 Pharmaceutical Intermediates – For use in advanced drug formulations or as an auxiliary compound in APIs.
🌱 Research-Grade Use – Ideal for clinical research, product development, and formulation trials.

🔹 OEM / ODM Capabilities
🧪 Custom Formulations – We develop formulas tailored for specific functions such as memory support, longevity, or skincare.
⚙️ Flexible Manufacturing – Scalable production capacity, from lab-scale samples to full commercial runs.
📦 Private Label & Branding – White-label or branded packaging in multiple sizes and material options.
📊 Full Documentation Support – Technical dossiers, COA, MSDS, and batch reports included with every order.
🔍 Regulatory & Market Entry Assistance – Guidance on regulatory requirements in EU, US, Middle East, and Asia.
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Standard plant extract series
| Item No | Product name | Active ingredients | Specification | Item No | Product name | Active ingredients | Specification | |
| 1 | Ginkgo Biloba Extract | Flavonoids,Lactones | 24%,6% | 54 | Mangosteen Extract | AlphaMangostina | 10-90% | |
| 2 | Shitake Mushroom Extract | Polysaccharides (UV) | 30%, 40%,50% | 55 | RoseHipExtract | Flavones | 1-20% | |
| 3 | Ivy Leaf Extract | Total Hederasaponins | 5%-60% | 56 | Schisandra Berry Extract | Schizandrins | 2-9% | |
| 4 | Ginseng Extract | Ginsenosides | 5%-80% | 57 | Cassia Seed Extract | Anthaquinone | 3% | |
| 5 | Ginger Extract | Gingerols | 5%,10%,25% | 58 | Soybean Extract | soy lsoflavones | 40% | |
| 6 | Rhodiola Rosea Extract | Salidroside, Rosavins | 3%-98%,3% | 59 | Chaga Extract Powder | Polysaccharides | 50% | |
| 7 | Ganoderma Extract | Polysaccharides (UV) | 30%,40%,50% | 60 | Hericium Erinaceus Extract | Polysaccharides | 30% | |
| 8 | Red Clover Extract | Total Isoflavones | 8%,10%,20%,40% | 61 | Trametes Versicolor Extract | Polysaccharides | 30% | |
| 9 | Grape Seed Extract | OPC | 95% | 62 | Cordyceps Militaris Extract | Polysaccharides | 30% | |
| 10 | Turmeric Extract | Curcumin | 95% | 63 | Ginkgo Biloba Extract | Ginkgo Flavonoids | 24% | |
| 11 | Quercetin | Quercetin | 95% | 64 | Angelica Sinensis Extract | Ferulic Acid | 1% | |
| 12 | Rutin | Rutin | 95% | 65 | Eleuthero Extract | Eleutherosides | 0.8% | |
| 13 | Diosmin | Diosmin | 90% | 66 | Gymostemma Extract | Gypenosides | 80% | |
| 14 | Hespridin | Hespridin | 90% | 67 | Hawthorn Extract | Proanihocyanidins | 20% | |
| 15 | Marigold Extract | Lutein / Zeaxanthin | 2%-80% | 68 | Ephedra Extract | Ephedrine | 8% | |
| 16 | Griffonia Simplicifolia Extract | 5-HTP | 10%-99% | 69 | Olive Leaf Extract | Oleuropein | 20% | |
| 17 | Kava Extract | Kavalactones | 30%,50%,70% | 70 | Centella Asiatica Extract | Asiaticoside | 40% | |
| 18 | Hawthorn Extract | Flavonoids | 2%,50% | 71 | Calendula Extract | Lutein | 5% | |
| 19 | Hibiscus Flower Extract | Anthocyanins | 5%-25% | 72 | Chamomile Extract | Aigenin | 1% | |
| 20 | Lion’s Mane Mushroom Extract | Polysaccharides (UV) | 30%,40%,50% | 73 | Senna Leaf Extract | Sennosides | 20% | |
| 21 | Maitake Mushroom Extract | Total Sugars (UV) | 30%,40%,50% | 74 | Chicory Extract | lnulin | 20% | |
| 22 | Mangosteen Extract | α-Mangostin | 10%-98% | 75 | Panax Notoginseng Extract | Notognsenosides | 5% | |
| 23 | Apple Cider Vinegar Powder | Apple Cider Vinegar Powder | 5%-50% | 76 | Polygonum Cuspidatum Extract | Resvetrol | 10-98% | |
| 24 | Yucca Extract | Saponins | 10%~98% | 77 | Kudzu root extract | puerarin | 15-98% | |
| 25 | Broccoli Extract | Glucoraphanin | 1%-20% | 78 | Scutellaria Extract | Baicalin | 85% | |
| 26 | Semen Ziziphi Spinosae Extract | Saponins | 1%-10% | 79 | Mulberry Leaf Extract | Sodium copper chlorophylin | 99% | |
| 27 | Echinacea Purpurea Extract | Chicoric Acid | 1%-4% | 80 | Alpha Lipoic Acid | Alpha Lipoic Acid | 99% | |
| 28 | Eucommia Leaf Extract | Chlorogenic Acid | 5%-98% | 81 | Coenzyme Q10 | Coenzyme Q10 | 98% | |
| 29 | Senna Leaf Extract | Sennosides A+B | 6%,8%,10%,20%,30% | 82 | pymoloquinoine Qunone Diodum(sait pqq) | pymoloquinoine Qunone Diodum(sait pqq) | 99% | |
| 30 | Scutellaria Root Extract | Baicalin | 88% | 83 | B-Nicinamide mononucleotie(NMN) | B-Nicinamide mononucleotie(NMN) | 99% | |
| 31 | Bitter Apricot Extract | Amygdalin | 98% | 84 | Astragalus Extract | Astragalus polysaccharides | 5-98% | |
| 32 | Soapnut Extract | Sapindus Saponins | 30%-80% | 85 | Scutellaria Extract | Scutellaria polysaccharide | 30%,50%,70% | |
| 33 | Pine Bark Extract | OPC | 95% | 86 | Green Tea Extract | Green Tea polyphenols | 50-98% | |
| 34 | Berbcrine Hydrochloride | Berberine Hydrochloride | 97% | 87 | GRAPE SKIN EXTRACT | Resveratrol | 5-20% | |
| 35 | Black Garlic Extract | Allicin | 1%-5% | 88 | Grape Seed Extiact | Proanthocyanidins | 95% | |
| 36 | Centella Asiatica Extract | Asiaticoside | 10%-70% | 89 | Turmeric Extract | Curcumin | 95% | |
| 37 | Aloe Yera GelFreeze Dried Powder | Freeze-Dried Aloe Vera Gel Powder | 50:1,100:1,200:1 | 90 | PanaxGinsengExtract | Ginsenosides | 10-80% | |
| 38 | Magnolia Bark Extract | Honokiol | 50%-98% | 91 | Pomegranate Extiact | Ellagic ACid | 40-90% | |
| 39 | Cyanotis Arachnoidea Extract | Ecdysterone | 2%-90% | 92 | Elderberry Extract | Anthocyanidin | 1-25% | |
| 40 | Epimedium Extract | Icariin | 1%-98% | 93 | Passiflora incarnate Extract | Flavone | 5% | |
| 41 | Cactus Extract | Polysaccharides | 10%-30% | 94 | Shiitake Mushroom Extract | Shiitake mushrooms | 10-50% | |
| 42 | Chaga Mushroom Extract | Polysaccharides (UV) | 30%, 40%,50% | 95 | Ganoderma lucidum Extract | Ganoderma lucidum | 10-50% | |
| 43 | Cistanche Desertcola Extract | Total Glycosides | 20%-80% | 96 | white willow Bark extract | Salicin | 15-98% | |
| 44 | Green Tea Extract | EGCG | 30%-98% | 97 | Rhodiola Rosea Extract | Salidroside | 1-3% | |
| 45 | Apple Exttact | Polyphenols | 1-70% | 98 | Marigold Flower Extract | Lutein | 5-20% | |
| 46 | Bilbery Leat Extract | Flavones | 1-20% | 99 | Milk Thistle Extract | Sillymarin | 80% | |
| 47 | Cinnamon Bark Extract | Flavones | 1-30% | 100 | wild Yam Extract | Diosgenin | 20-98% | |
| 48 | Pine Bark Extract Powder | Proanthocyuanidins | 95% | 101 | Echinacea purpurea Extract | Chicory Acid | 1-3% | |
| 49 | Epimedium Extract | ICcarins | 1-98% | 102 | Sophora Japonica Extract | Rutin | 95% | |
| 50 | Grapeseed Extract | CProarthocyanidins | 95% | 103 | Sophora Japonica Extract | Quercetin | 95% | |
| 51 | Goji Extract | Povsaccharides | 5-60% | 104 | Aloe vera Extract | Aloin | 20% | |
| 52 | Rosemary Extract | RosemaryAcid | 5% | 105 | Haematococcus pluvialis Extract | Astaxanthin(Powder/oil) | 5% | |
| 53 | Horsetail Extract | silica | 7% | 106 | Tomato Extract | LYCOPENE(Powder/oil) | 5%,10% |
Frequently Asked Questions (FAQ) – Fisetin Powder 98%
1. What is Fisetin Powder 98%?
Fisetin Powder is a premium-grade, neuroprotective flavonoid extracted and standardized to high purity (HPLC-verified 98%, actual content 91%). It is known for antioxidant, anti-inflammatory, and cognitive-supporting properties.
2. What are the main applications of Fisetin?
Fisetin is commonly used in:
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Functional foods and dietary supplements
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Nutraceuticals for brain health and cognitive support
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Skincare and cosmetic formulations
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Advanced pharmaceutical or botanical research
3. How is Fisetin standardized?
The powder is standardized using external references, ensuring actual content ≥91% with HPLC verification, and external standard ≥80%.
4. What certifications does your Fisetin carry?
Our product is certified cGMP, HACCP, Halal, Kosher, IAF, and verified via SGS third-party testing, ensuring quality, safety, and regulatory compliance.
5. Is Fisetin safe for dietary supplement and cosmetic use?
Yes. Its high purity, standardized content, and strict production protocols make it suitable for dietary supplements, nutraceuticals, functional foods, and skincare applications.
6. Do you offer OEM/ODM services?
Yes. We provide full OEM/ODM solutions, including bulk supply, formulation support, private labeling, and custom packaging for global industrial clients.
7. What forms and concentrations are available?
Fisetin is supplied as a fine powder standardized to 98% purity, with bulk supply and customizable formats available for industrial applications.
8. How should Fisetin be stored?
Store in a cool, dry, and well-ventilated area, protected from light and moisture to maintain stability and bioactivity.
9. Can samples be requested before bulk purchase?
Yes. Samples are available for R&D, quality verification, and formulation evaluation prior to placing bulk orders.
10. What is the typical lead time for orders?
Standard bulk orders usually ship within 3–7 business days, while OEM/ODM customized orders may require additional production time depending on specifications.





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