α-Ketoglutaric Acid (AKG) Anti-Aging & Cellular Support

α-Ketoglutaric Acid (AKG) Anti-Aging & Cellular Support

AKG Antioxidant & Longevity Ingredient

α-Ketoglutaric Acid (AKG) – Premium Functional Ingredient for Longevity, Antioxidant, and Cellular Health

α-Ketoglutaric Acid (AKG) is a dicarboxylic acid with a ketone group, naturally occurring as a key intermediate in the tricarboxylic acid (TCA) cycle. AKG is widely recognized for its versatile physiological benefits, including cellular energy support, antioxidant defense, anti-aging, immune modulation, muscle preservation, and metabolic balance.

AKG participates in amino acid metabolism by reacting with ammonia to produce glutamate, which can further form glutamine, supporting protein synthesis and nitrogen balance. It also contributes to succinate production via hydration, generating CO₂ and H₂O, and scavenging reactive oxygen species (ROS). AKG serves as a critical energy donor for intestinal and other metabolically active cells, and helps maintain cellular redox homeostasis.

    Description

    Premium Alpha-Ketoglutaric Acid (AKG) Powder - TCA Cycle Intermediate for Longevity & Cellular Energy - B2B Supplier
    Alpha-Ketoglutaric Acid (AKG): Key cellular energy metabolite for anti-aging, sports nutrition & immune support. cGMP certified bulk ingredient for global B2B markets.

    Product Specifications

    Product Name: α-Ketoglutaric Acid (AKG)
    CAS No.: 328-50-7
    Molecular Formula: C5H6O5
    Molecular Weight: 146.11
    Appearance: White crystalline powder
    Solubility: Soluble in water, slightly soluble in ethanol
    pH: Acidic (pKa ≈ 2.5 & 4.3)
    Stability: Hygroscopic, moderately unstable, easily oxidized
    Odor: Slight acidic smell
    Packaging: 1kg/bag, 25kg/drum
    Minimum Order Quantity: 25kg
    Global Markets: North America, South/Central America, Europe, Oceania, Asia, Middle East, Africa
    Samples Available: Yes

    Key Benefits

    1. Anti-Aging & Longevity

    1.1AKG is considered a metabolic anti-aging compound. Studies show AKG may promote lifespan extension and healthy aging by modulating cellular energy metabolism, epigenetic regulation, and oxidative stress pathways.

    2. Cellular Energy & Muscle Support

    2.1Generates ATP via TCA cycle, enhancing muscle energy and endurance.
    2.2Supports muscle growth and protein synthesis.
    2.3Improves post-surgical recovery and tissue repair.

    3. Antioxidant & ROS Scavenging

    3.1Maintains redox balance and reduces oxidative stress.
    3.2Protects neurons, intestinal cells, and other tissues from oxidative damage.
    3.3Enhances the body’s antioxidant defense system.

    4. Bone, Gut & Metabolic Health

    4.1Supports gut mucosal cell integrity.
    4.2Modulates amino acid metabolism and nitrogen utilization.
    4.3Contributes to glucose metabolism regulation, alleviating hyperglycemia in diabetic conditions.

    5. Applications Across Industries

    5.1Nutraceuticals & Functional Foods: Anti-aging, longevity, and energy supplements.
    5.2Cosmetics & Personal Care: Anti-aging creams, serums, and formulations supporting collagen and skin barrier function.
    5.3Pharmaceuticals: Adjunct therapy for metabolic, degenerative, and oxidative stress-related conditions.
    5.4Animal Nutrition: Enhances growth, immunity, bone development, and intestinal health in livestock.

    Why Choose Our AKG

    ✅ Advanced Production & High Purity: Produced under state-of-the-art manufacturing equipment, ensuring low impurities and consistent quality.
    ✅ Multi-Functional Benefits: Supports cellular energy, antioxidant defense, muscle growth, immune function, and skin health.
    ✅ Research-Backed & Bioactive: Scientifically validated for anti-aging, metabolic regulation, and ROS scavenging.
    ✅ Wide Industry Applications: Ideal for nutraceuticals, functional foods, cosmetics, pharmaceuticals, and animal nutrition.
    ✅ Global Supply & Customization: Flexible OEM/ODM services, regulatory support, and logistics assistance for international B2B clients.

    α-Ketoglutaric Acid (AKG) is a highly bioactive, multifunctional ingredient for anti-aging, cellular energy, antioxidant defense, and metabolic health. Its versatile applications, combined with high purity and advanced production, make it a premium choice for global manufacturers, brands, and distributors in health, beauty, and nutrition industries.

     

    α-Ketoglutaric Acid (AKG) – FAQ

    1. Product Overview

    Q1: What is α-Ketoglutaric Acid (AKG)?
    A: α-Ketoglutaric Acid (AKG) is a naturally occurring dicarboxylic acid with a ketone group and a key intermediate in the tricarboxylic acid (TCA) cycle. It plays a vital role in cellular energy metabolism, amino acid synthesis, and antioxidant defense.

    Q2: What are the main benefits of AKG?
    A: AKG offers multiple health benefits, including:

    • Supporting cellular energy and metabolism

    • Acting as an antioxidant and scavenger of reactive oxygen species (ROS)

    • Promoting anti-aging and longevity

    • Supporting muscle preservation and nitrogen balance

    • Modulating immune function

    • Maintaining overall metabolic homeostasis

    Q3: How does AKG work in the body?
    A: AKG participates in amino acid metabolism by reacting with ammonia to form glutamate, which can further convert into glutamine to support protein synthesis and nitrogen balance. It also contributes to succinate production while scavenging ROS, helping maintain cellular redox balance and energy supply.


    2. Applications & Functional Benefits

    Q4: Can AKG support muscle health and exercise performance?
    A: Yes. AKG provides energy and supports nitrogen balance, helping reduce muscle breakdown, enhance recovery, and maintain muscle function, making it a valuable ingredient in sports nutrition and fitness supplements.

    Q5: How does AKG support longevity and anti-aging?
    A: By promoting cellular energy metabolism, reducing oxidative stress, and regulating aging-related pathways, AKG helps maintain cellular and tissue health, supporting overall longevity.

    Q6: Is AKG an antioxidant?
    A: Yes. AKG can neutralize reactive oxygen species (ROS), protecting cells from oxidative damage and promoting overall cellular health.

    Q7: Does AKG support gut or intestinal health?
    A: Yes. AKG serves as an important energy source for intestinal and other metabolically active cells, supporting gut barrier integrity and healthy digestion.


    3. Safety & Usage

    Q8: Is AKG safe for daily consumption?
    A: AKG is naturally present in the human body and widely used as a dietary supplement. It is generally recognized as safe when consumed according to recommended guidelines.

    Q9: What forms of AKG are available?
    A: AKG is available as the free acid, calcium salt (Ca-AKG), or other mineral salts, suitable for powders, tablets, capsules, and functional food formulations.

    Q10: What is the recommended dosage of AKG?
    A: Dosage depends on the formulation and intended effect. Clinical studies commonly use daily intakes ranging from 1–5 grams. Always follow product instructions or consult a healthcare professional.


    4. Technical & Industry Information

    Q11: How is AKG produced?
    A: AKG can be manufactured via microbial fermentation or chemical synthesis. High-purity, pharmaceutical-grade AKG is suitable for dietary supplements, functional foods, and nutraceutical applications.

    Q12: Is AKG stable in formulations?
    A: AKG is generally stable in powder form. Proper storage in a dry, cool environment away from light and moisture ensures product stability and efficacy.

    Q13: Which industries can benefit from AKG?
    A: AKG is widely applied in:

    • Dietary supplements and nutraceuticals

    • Functional foods and beverages

    • Sports nutrition and fitness products

    • Anti-aging and wellness formulations


    ✅ This FAQ is optimized for global B2B buyers searching for AKG supplement, α-Ketoglutaric Acid, longevity ingredient, antioxidant, muscle health support, helping increase visibility and credibility for your brand.

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