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Acetylated Sodium Hyaluronate 20k-50kDa · Oil Phase Hydration

Acetylated Sodium Hyaluronate 20-50kDa · Deep Hydration

Acetylated Sodium Hyaluronate (Molecular Weight 20,000–50,000 Da) is a next-generation hyaluronic acid derivative produced through targeted acetylation technology, achieving precise control over molecular weight and substitution degree. Unlike conventional HA, which is only water-soluble, acetylated HA exhibits lipophilic and oleophilic properties, allowing dual-phase hydration and enhanced skin barrier repair. Its amphiphilic structure enables deeper penetration, long-lasting moisture retention, and improved elasticity, making it ideal for high-end oil-based formulations such as facial oils, creams, sunscreens, and medical oil-based dressings.

This ingredient is highly resistant to hyaluronidase, showing 13 times the enzyme resistance of standard sodium hyaluronate, effectively protecting the dermis from degradation and intrinsic aging. In skin penetration tests, acetylated sodium hyaluronate reaches depths up to 100μm, significantly deeper than standard HA. By delivering moisture and bioactive molecules deeper into the skin, it helps improve dryness, roughness, and skin suppleness.

Our products are manufactured under strict international standards, including cGMP, ISO 9001, ISO 22000, ISO 13485, HACCP, Halal, FSSC 22000, FDA, REACH, and COSMOS certifications, ensuring each batch’s safety, stability, and consistency. We provide a full range of standard and customized hyaluronic acid and chondroitin sulfate materials, widely used in cosmetics, personal care, nutrition, functional foods, healthcare, pharmaceuticals, and research applications worldwide.