Ergothioneine (EGT) Natural Antioxidant & Cellular Protection
Ergothioneine (EGT) Natural Antioxidant & Cellular Protection
High-Purity Ergothioneine (EGT) Antioxidant Ingredient
Ergothioneine (EGT) is a rare, naturally occurring chiral amino acid with exceptional antioxidant and cell-protective functions. Chemically known as 2-thio-L-histidine trimethylbetaine, EGT is a powerful natural antioxidant featuring a unique thione–thiol tautomeric structure that provides outstanding stability against oxidation. Unlike other antioxidants such as glutathione, EGT remains stable under physiological pH, offering long-lasting cellular protection.
Humans cannot synthesize Ergothioneine and must obtain it externally, making it a vital micronutrient with diverse health benefits. Produced with advanced fermentation and purification technology under ISO22000, HACCP, and FDA standards, our EGT features ultra-high purity, excellent bioavailability, and consistent quality suitable for food, pharmaceutical, cosmetic, and nutraceutical applications.
Description

Key Features & Specifications
Product Name: Ergothioneine (EGT)
Chemical Name: 2-Thio-L-histidine trimethylbetaine
CAS No.: 497-30-3
Molecular Formula: C9H15N3O2S
Molecular Weight: 229.30
Appearance: White crystalline powder
Purity: ≥99% (High-Purity Grade)
Solubility: Soluble in water
Shelf Life: 24 months
Storage: Store in a sealed, dry, and cool place away from light
Certifications: ISO22000, HACCP, FDA, Halal, Kosher
Packaging: 1 kg/bag, 25 kg/drum or customized
Functional Benefits
1.Powerful Antioxidant Activity: Neutralizes free radicals (O₂·⁻, H₂O₂, ·OH, ¹O₂), protects DNA and mitochondria, and enhances overall oxidative defense.
2.Cellular Protection & Anti-Aging: Reduces oxidative damage, prevents collagen degradation, and supports long-term skin and cell health.
3.Anti-Inflammatory & Immune Regulation: Inhibits pro-inflammatory cytokines and enhances immune cell balance.
4.Neuroprotective Effects: Promotes neuron survival, supports brain function, and may prevent neurodegenerative diseases.
5.Metabolic & Cardiovascular Support: Improves insulin sensitivity, protects against cardiovascular stress, and reduces tissue fibrosis.
6.Heavy Metal Detoxification: Chelates toxic metals (e.g., copper, mercury), minimizing oxidative stress and promoting detoxification.
7.UV & Skin Protection: Activates the PI3K/Akt/Nrf2 pathway, reducing UV-induced oxidative stress and preventing photoaging.
Applications
1.Nutraceuticals & Functional Foods: Used in anti-aging, immunity-boosting, and metabolic health supplements.
2.Cosmetics & Skincare: Protects skin from UV damage, supports collagen synthesis, and improves radiance.
3.Pharmaceuticals: Potential therapeutic applications for diabetes, renal disease, and neuroprotection.
4.Food & Beverage Industry: Enhances nutritional value as a natural antioxidant additive.
5.Animal Nutrition: Improves livestock and pet health through antioxidant and cellular support functions.
6.Biotechnology: Used in organ preservation, cell storage, and biomedical research.
Why Choose Our Ergothioneine (EGT)?
1.High Purity & Stability: Advanced fermentation and purification ensure ultra-pure EGT with excellent oxidative stability.
2.Scientifically Proven Mechanisms: Demonstrated activation of PI3K/Akt/Nrf2 pathway for oxidative stress defense and collagen protection.
3.Versatile Applications: Suitable for food, health, cosmetic, and pharmaceutical industries.
4.Comprehensive Certifications: Produced under ISO22000, HACCP, and FDA standards with Halal and Kosher compliance.
5.Global Supply Capability: Exported worldwide to Europe, North America, Japan, and Southeast Asia.
6.OEM & ODM Support: Customized formulation, blending, and packaging services available.
🧾 Ergothioneine (EGT) – Frequently Asked Questions (FAQ)
1. What is Ergothioneine (EGT)?
Answer:
Ergothioneine (EGT) is a naturally occurring amino acid derivative with potent antioxidant and cytoprotective properties. It is biosynthesized by certain fungi and bacteria and accumulates in human tissues through dietary intake. EGT protects cells and mitochondria from oxidative stress, inflammation, and aging-related damage.
2. What is the source of your Ergothioneine?
Answer:
Our Ergothioneine is produced via advanced microbial fermentation technology, ensuring a sustainable, natural, and non-synthetic origin. This method guarantees high purity (≥99%) and consistent quality suitable for nutraceutical, cosmetic, and pharmaceutical applications.
3. What are the main benefits of Ergothioneine?
Answer:
EGT acts as a powerful antioxidant that neutralizes free radicals, supports cellular longevity, protects DNA and mitochondria, regulates inflammation, and enhances skin and brain health. It also supports cardiovascular, metabolic, and immune functions.
4. How does Ergothioneine work in the body?
Answer:
EGT is taken up by cells through a specific transporter (OCTN1) and accumulates in high-stress tissues such as the liver, kidneys, eyes, and brain. It activates the PI3K/Akt/Nrf2 signaling pathway, boosting antioxidant enzyme activity and protecting against oxidative and UV-induced stress.
5. What are the common applications of Ergothioneine?
Answer:
-
Nutraceuticals & Functional Foods: Anti-aging, metabolic, and immune-support supplements
-
Cosmetics & Skincare: Anti-oxidation, UV protection, and collagen support
-
Pharmaceuticals: Research on diabetes, neuroprotection, and renal health
-
Food & Beverage: Natural antioxidant ingredient
-
Animal Nutrition & Biotechnology: Cellular and organ protection
6. What purity and specifications are available?
Answer:
Our standard specification is ≥99% purity (High-Purity Grade) with white crystalline powder appearance. We also offer customized grades and packaging formats (1 kg/bag or 25 kg/drum).
7. How should Ergothioneine be stored and handled?
Answer:
Store in a sealed, dry, and cool place away from direct sunlight and humidity. Under proper storage conditions, the product maintains stability for 24 months.
8. Is Ergothioneine safe for human consumption?
Answer:
Yes. EGT is a naturally occurring dietary antioxidant and has been recognized as safe in multiple studies. Our EGT complies with ISO22000, HACCP, FDA, Halal, and Kosher standards.
9. What dosage is recommended in formulations?
Answer:
Recommended dosage depends on the application:
-
Nutraceuticals: typically 5–30 mg/day
-
Cosmetics: 0.01–0.2% concentration in formulations
(Exact dosage should be determined based on regional regulations and formulation design.)
10. Do you provide OEM or customized formulation support?
Answer:
Yes. We offer OEM/ODM services, including custom blending, encapsulation, and packaging, to meet the needs of global nutraceutical, cosmetic, and pharmaceutical brands.
11. What makes your Ergothioneine superior to others?
Answer:
-
Ultra-high purity (≥99%)
-
Stable and bioavailable form
-
Fermentation-derived (non-synthetic)
-
Proven efficacy via PI3K/Akt/Nrf2 pathway
-
Full certification (ISO, HACCP, FDA, Halal, Kosher)
-
Global export capability and technical support
12. Can Ergothioneine be combined with other antioxidants?
Answer:
Yes. EGT works synergistically with antioxidants such as Vitamin C, Glutathione, Coenzyme Q10, and Astaxanthin, enhancing overall oxidative protection and skin health effects.
Reviews
There are no reviews yet.