Acetylated Sodium Hyaluronate (AcHA) is a high-performance derivative of conventional sodium hyaluronate (HA), obtained through an acetylation reaction. This modification introduces acetyl groups to HA, enhancing its lipophilicity, skin affinity, and adsorption properties. As a result, AcHA exhibits superior bioactivity, allowing it to deeply penetrate the stratum corneum, adhere firmly to the skin surface, and provide long-lasting hydration. Its innovative structure ensures that water is retained in the skin for extended periods, creating a double moisturizing effect that is highly valued in modern skincare formulations.
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Premium 4D HA Solution for Full-Skin Moisturization & Repair
4D Sodium Hyaluronate Solution Deep & Surface Hydration
4D Multiple Sodium Hyaluronate Solution is a state-of-the-art skin care ingredient that combines four distinct types of sodium hyaluronate, each designed to act on specific skin layers, from the stratum corneum to the dermis. The formulation includes high molecular weight sodium hyaluronate, cross-linked HA polymers, acetylated HA (AcHA), and hydrolyzed ultra-low molecular weight HA. Together, these multiple forms of HA deliver comprehensive, multi-dimensional hydration and skin repair benefits.
Upon application, each HA type penetrates targeted skin layers: high molecular weight HA forms a protective layer on the surface, preventing water loss and providing immediate moisturization; cross-linked HA polymers create a long-lasting hydration shield, enhancing moisture retention and skin barrier protection; acetylated HA, with enhanced lipophilicity, adheres firmly to the skin, repairing damaged epidermal cells and improving elasticity; hydrolyzed low molecular weight HA penetrates deeply into the dermis for intensive hydration and anti-inflammatory support. This unique 4D mechanism ensures that both surface and deep skin layers are nourished, hydrated, and rejuvenated.
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Hyaluronic Acid Superior Hydration & Skin Repair
Hyaluronic Acid (HA), also known as Sodium Hyaluronate in its salt form, is a naturally occurring linear polysaccharide widely distributed in human and animal tissues. HA is present in the vitreous humor of the eyes, synovial fluid of joints, umbilical cord, and skin. As an essential biological molecule, HA plays a crucial role in maintaining tissue hydration, elasticity, and overall skin health. Its concentration is highest during the embryonic stage and gradually decreases with age. For instance, at 20 years old, HA levels are considered 100%, dropping to approximately 65% by age 30, 45% by age 50, and 25% by age 60. Patients with premature aging or progeria show a significantly reduced HA content, which contributes to common aging symptoms such as dryness, wrinkles, and loss of skin elasticity.
Chemically, HA is an acidic polysaccharide composed of repeating disaccharide units of D-glucuronic acid and N-acetyl-D-glucosamine. When the carboxyl group of HA is neutralized with sodium ions, it forms sodium hyaluronate, which is more soluble in water and widely used in cosmetic, pharmaceutical, and nutritional applications. Despite this chemical distinction, HA and sodium hyaluronate share the same backbone structure, and both are often colloquially referred to as “hyaluronic acid” or “Hyaluronan.”
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