Palmitoyl Hexapeptide-12 Advanced Anti-Wrinkle & Skin Firming Peptide
Palmitoyl Hexapeptide-12 Advanced Anti-Wrinkle & Skin Firming Peptide
Palmitoyl Hexapeptide-12 for Wrinkle Reduction
Palmitoyl Hexapeptide-12 is a potent anti-wrinkle and skin-conditioning peptide, widely recognized for its ability to stimulate collagen and elastin synthesis, restore skin elasticity, and reduce visible signs of aging. It belongs to the family of signal peptides, designed to mimic natural sequences that activate fibroblast activity within the skin’s extracellular matrix.
Structurally, Palmitoyl Hexapeptide-12 consists of a short chain of six amino acids conjugated with palmitic acid, which enhances lipophilicity and skin penetration. This peptide sequence (Val-Gly-Val-Ala-Pro-Gly) acts as a biological messenger to promote skin firmness, smoothness, and resilience. Scientific studies have shown that it improves skin density, reduces fine lines, and supports long-term skin repair and rejuvenation.
It is highly stable, easy to formulate, and compatible with most cosmetic emulsions, serums, and creams. Palmitoyl Hexapeptide-12 is a key ingredient in premium anti-aging, lifting, and skin repair formulations, suitable for daily use in both professional and consumer skincare products.
Our product is manufactured under GMP, ISO9001, and HACCP certified conditions, ensuring high purity, stability, and consistent bioactivity. Each batch undergoes strict HPLC and MS analysis to verify structure and performance.
Description
Product Name: Palmitoyl Hexapeptide-12
CAS No.: 171263-26-6
Molecular Formula: C₄₀H₇₈N₈O₉
Molecular Weight: Approx. 799.1 Da
Molecular Weight Range: 780–820 Da
Appearance: White to off-white powder
Functions:
Stimulates collagen and elastin synthesis
Improves skin firmness and elasticity
Reduces fine lines and wrinkles
Restores smoothness and tone
Enhances hydration and barrier function
Promotes a youthful, radiant complexion
Solubility: Soluble in water, ethanol, and propylene glycol
Stability: Excellent chemical stability under recommended conditions
Applications
1.Anti-aging serums and firming creams
2.Wrinkle-reduction eye and face creams
3.Lifting and tightening emulsions
4.Night repair treatments
5.Professional-grade skincare formulations
6.Post-treatment recovery products
Storage and Shelf Life
Store in a cool, dry, and dark environment (2–8°C). Keep container tightly sealed and protect from humidity. Avoid exposure to high temperatures and direct sunlight. Shelf life is 24 months under proper storage conditions.
Why Choose Us
1.Professional Peptide Manufacturer: Extensive expertise in peptide synthesis and formulation support.
2.Certified Quality: Produced under GMP, ISO9001, HACCP, and Halal standards.
3.High Purity Assurance: Verified by HPLC with ≥98% purity.
4.Global OEM/ODM Service: Custom solutions for skincare, personal care, and cosmeceutical brands.
5.Full Export Support: End-to-end logistics, customs clearance, and international shipping.
6.Expert R&D Team: Providing technical formulation assistance and stability optimization.
Our Product Advantages
1.Proven efficacy in wrinkle reduction and skin firming
2.Lipid-modified structure enhances skin absorption
3.Clinically supported to promote collagen remodeling
4.Non-irritating, suitable for sensitive skin types
5.Excellent stability and solubility in cosmetic formulations
6.Compatible with other anti-aging ingredients such as hyaluronic acid, niacinamide, and peptides
Palmitoyl Hexapeptide-12 – Frequently Asked Questions (FAQ)
1. What is Palmitoyl Hexapeptide-12?
Palmitoyl Hexapeptide-12 is a bioactive signal peptide composed of six amino acids linked to a palmitic acid chain. It is designed to stimulate collagen and elastin synthesis, helping to restore skin firmness, elasticity, and smoothness. It is widely used in anti-aging and skin-repair formulations.
2. How does Palmitoyl Hexapeptide-12 work on the skin?
This peptide acts as a biological messenger, mimicking natural sequences that activate fibroblast activity in the skin’s extracellular matrix. By signaling cells to produce more collagen and elastin, it helps reduce wrinkles, improve skin density, and enhance long-term rejuvenation.
3. What are the main cosmetic benefits of Palmitoyl Hexapeptide-12?
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Boosts collagen and elastin synthesis
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Improves skin firmness and elasticity
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Reduces fine lines and wrinkles
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Enhances skin smoothness and density
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Supports long-term skin repair and resilience
4. In which types of formulations can it be used?
Palmitoyl Hexapeptide-12 is suitable for:
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Anti-aging creams and serums
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Firming and lifting products
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Skin repair and rejuvenation treatments
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Moisturizing and nourishing emulsions
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Eye contour and neck care formulas
5. What is the recommended usage level in formulations?
The typical recommended dosage is 0.001–0.05%, depending on formulation type and desired effect. It should be incorporated at temperatures below 40°C to preserve peptide stability and activity.
6. Is Palmitoyl Hexapeptide-12 stable in formulations?
Yes. It is a highly stable and lipophilic peptide, easily incorporated into emulsions, serums, and creams. Its palmitoyl modification enhances skin penetration and formulation compatibility.
7. Is it safe for all skin types?
Yes. Palmitoyl Hexapeptide-12 is non-irritating, hypoallergenic, and suitable for all skin types, including sensitive skin. It is paraben-free and non-animal derived.
8. How should Palmitoyl Hexapeptide-12 be stored?
Store in a cool, dry place, protected from light and moisture. For long-term stability, refrigeration at 2–8°C is recommended. Avoid repeated freeze–thaw cycles.
9. What is the purity and appearance of your product?
Purity: ≥98% (HPLC)
Appearance: White to off-white lyophilized powder
Solubility: Soluble in water and ethanol
10. What quality certifications and analysis do you provide?
Our Palmitoyl Hexapeptide-12 is manufactured under GMP, ISO9001, and HACCP standards. Each batch is tested using HPLC and Mass Spectrometry (MS) for identity, purity, and bioactivity. COA, MSDS, and TDS are available upon request.
11. What packaging sizes are available?
Standard packaging: 1g, 10g, 100g per vial, or customized according to your project needs. Bulk and OEM supply are available for large-scale production.
12. Can Palmitoyl Hexapeptide-12 be combined with other ingredients?
Yes. It is compatible with other peptides, hyaluronic acid, niacinamide, antioxidants, and botanical actives. Combining actives can enhance skin repair, hydration, and anti-aging performance.
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