Nonapeptide-1 Powder Advanced Whitening & Brightening Peptide
Nonapeptide-1 Powder Advanced Whitening & Brightening Peptide
Nonapeptide-1 Skin Brightening Peptide Supplier
Nonapeptide-1, also known as Melanostatine™-5, is a biomimetic peptide designed to regulate skin pigmentation and inhibit melanin synthesis. It is composed of nine amino acids (a nonapeptide) that act as a potent antagonist of the α-MSH (alpha-Melanocyte-Stimulating Hormone) receptor, thereby reducing the activation of tyrosinase and preventing melanin formation. This makes it a powerful and safe ingredient for skin-whitening, brightening, and anti-spot formulations in cosmetics and personal care products.
Derived through advanced peptide synthesis technology, Nonapeptide-1 provides targeted control over pigmentation, ideal for treating hyperpigmentation, age spots, freckles, and uneven skin tone. Unlike traditional whitening agents, this peptide works gently and effectively without causing irritation or cytotoxic effects, making it suitable for sensitive skin and long-term use.
Nonapeptide-1 is widely used in high-end whitening creams, serums, lotions, essence formulations, and brightening masks. It can also be incorporated into nutracosmetic and functional skincare products due to its stable structure and strong biological activity.
Description
Product Name: Nonapeptide-1
Synonyms: Melanostatine™-5, Skin Whitening Peptide
CAS Number: 158563-45-2
Molecular Formula: C₅₀H₆₈N₁₄O₁₃S
Molecular Weight: 1087.22 Da
Molecular Weight Range: 1000–1100 Da
Appearance: White to off-white powder
Purity: ≥98% (HPLC)
Solubility: Soluble in water
Storage Conditions: Store in a cool (2–8°C), dry, and dark place. Avoid repeated freeze-thaw cycles.
Shelf Life: 24 months when properly stored

Functions & Benefits
1.Whitening & Brightening: Inhibits α-MSH binding to melanocytes, reducing elanin synthesis.
2.Anti-pigmentation: Effectively lightens dark spots, freckles, and uneven skin tone.
3.Anti-aging & Radiance: Enhances skin clarity and luminosity, restoring a youthful glow.
4.Safe & Gentle: Non-toxic, non-irritating, suitable for all skin types including sensitive skin.
5.Synergistic Use: Works well with niacinamide, arbutin, and vitamin C derivatives.
Applications
1.Whitening and brightening creams
2.Anti-freckle and spot-reducing serums
3.Brightening essence and ampoules
4.Sunscreen formulations for post-UV care
5.Whitening masks and sheet mask formulations
6.Cosmeceutical and functional skincare
Our Product Advantages
1.High Purity & Bioactivity: Produced under GMP-grade synthesis with HPLC ≥98%.
2.Certified Quality: Our peptides comply with ISO9001, HACCP, GMP, and Halal standards.
3.OEM & ODM Services: Customized formulation, blending, and packaging for global cosmetic brands.
4.Strict Quality Control: Advanced peptide synthesis equipment and professional R&D team.
5.Fast Global Shipping: Rich export experience to Japan, Korea, Europe, and the Middle East.
6.Comprehensive After-sales Support: Technical guidance and stability testing assistance provided.
Why Choose Us?
1.Professional Manufacturer: Over 10 years of expertise in peptide and cosmetic raw material production.
2.Comprehensive Solutions: From R&D, synthesis, purification, testing, to export logistics, we provide one-stop service.
3.Quality Assurance: Products tested by HPLC, MS, and IR to ensure consistency and reliability.
4.Global Network: Trusted supplier for top cosmetic, skincare, and nutraceutical companies worldwide.
Storage & Handling
Keep sealed in an airtight container away from moisture, heat, and direct light. For long-term storage, freeze at -20°C. Reconstitute immediately before use. Avoid contamination during handling.
Nonapeptide-1 is a cutting-edge peptide whitening ingredient proven to effectively reduce melanin production and enhance skin brightness safely and gently. Supported by strong R&D capability, quality certifications, and OEM/ODM flexibility, our company delivers globally trusted peptide solutions for cosmetics, personal care, and skincare industries.
Nonapeptide-1 (Melanostatine™-5) FAQ
1. What is Nonapeptide-1?
Nonapeptide-1, also known as Melanostatine™-5, is a biomimetic peptide composed of nine amino acids. It is designed to regulate skin pigmentation by inhibiting melanin synthesis, making it an effective ingredient for skin brightening and anti-spot formulations.
2. How does Nonapeptide-1 work?
Nonapeptide-1 acts as a potent antagonist of the α-MSH (alpha-Melanocyte-Stimulating Hormone) receptor, reducing tyrosinase activation. This prevents melanin formation, leading to a more even skin tone and reduced appearance of dark spots.
3. What are the main benefits of Nonapeptide-1?
-
Brightens skin and reduces hyperpigmentation
-
Minimizes age spots, freckles, and uneven skin tone
-
Gentle and safe for sensitive skin
-
Suitable for long-term use without irritation
4. In which cosmetic products can Nonapeptide-1 be used?
Nonapeptide-1 is suitable for high-end whitening creams, serums, lotions, essences, and brightening masks. It can also be incorporated into functional skincare and nutracosmetic products.
5. Is Nonapeptide-1 safe for sensitive skin?
Yes. Unlike traditional whitening agents, Nonapeptide-1 is gentle and non-cytotoxic, making it safe for sensitive skin and long-term use.
6. How is Nonapeptide-1 produced?
Nonapeptide-1 is synthesized using advanced peptide synthesis technology, ensuring high purity, stability, and bioactivity.
7. Can Nonapeptide-1 be combined with other active ingredients?
Yes. Nonapeptide-1 is compatible with most skincare actives, including moisturizers, antioxidants, and anti-aging peptides, allowing formulators to create multifunctional products.
8. What concentration of Nonapeptide-1 is typically used in formulations?
Effective concentrations usually range from 0.01% to 0.1% depending on the product type and desired efficacy.
9. How long does it take to see results from Nonapeptide-1?
Visible improvement in skin tone and reduction of dark spots is generally observed after 4–8 weeks of regular use, depending on the formulation and individual skin type.
10. Why choose Nonapeptide-1 over traditional whitening agents?
Nonapeptide-1 provides targeted pigmentation control without harsh chemicals, reducing the risk of irritation and long-term skin damage. It is ideal for high-end, safe, and effective skin-brightening products.





Reviews
There are no reviews yet.