Acetyl Tetrapeptide-5 Anti-Aging, Firming & Moisturizing Cosmetic Peptide
Acetyl Tetrapeptide-5 Anti-Aging, Firming & Moisturizing Cosmetic Peptide
Acetyl Tetrapeptide-5 Eye Contour & Anti-Aging Peptide
Acetyl Tetrapeptide-5, also known as Eyeseryl® peptide, is a clinically studied bioactive peptide composed of four amino acids designed to target skin aging signs such as puffiness, dark circles, and loss of elasticity. With its excellent anti-aging, anti-edema, and moisturizing properties, this peptide helps improve skin firmness, elasticity, and hydration, especially in delicate eye-area formulations.
Scientific studies have demonstrated that Acetyl Tetrapeptide-5 reduces under-eye puffiness, prevents glycation, and enhances lymphatic circulation, resulting in smoother, brighter, and more youthful-looking skin. Its high biocompatibility makes it ideal for sensitive and mature skin care formulations.
Description
Product Name: Acetyl Tetrapeptide-5
CAS No.: 820959-17-9
Molecular Formula: C20H28N8O7
Molecular Weight: 492.49 g/mol
Molecular Weight Range: 490–495 Da
Appearance: White to off-white powder
Solubility: Soluble in water
Storage: Store in a cool, dry, and dark place below 25°C. Avoid light, moisture, and heat.
Shelf Life: 24 months under recommended storage conditions

Functions & Benefits
1.Reduces Eye Puffiness & Dark Circles: Enhances lymphatic drainage, reducing water accumulation and pigmentation around the eyes.
2.Anti-Aging & Firming: Boosts skin elasticity and firmness by inhibiting glycation and stimulating collagen synthesis.
3.Moisturizing Effect: Improves skin hydration through strengthening the extracellular matrix (ECM) and retaining moisture.
4.Anti-Glycation Protection: Prevents protein cross-linking that leads to dullness and loss of elasticity.
5.Soothing & Skin-Conditioning: Calms tired, fatigued skin and enhances comfort for sensitive areas.
Applications
1.Eye Care Products: Eye creams, serums, and gels targeting puffiness and dark circles.
2.Anti-Aging Formulations: Firming serums, lifting creams, and rejuvenating masks.
3.Hydrating Skincare: Moisturizers and anti-fatigue treatments for all skin types.
4.Sensitive Skin Products: Gentle formulations that improve microcirculation and strengthen the skin barrier.
Mechanism of Action
Acetyl Tetrapeptide-5 works by modulating microvascular permeability and inhibiting glycation reactions that damage collagen and elastin. It enhances the elasticity and compactness of the skin by improving the functionality of structural proteins in the extracellular matrix. The peptide also promotes water retention and circulation, leading to visibly smoother and firmer skin—particularly effective in the periorbital (eye) area.
Why Choose Our Acetyl Tetrapeptide-5?
1.High Purity & Bioactivity: Produced through advanced solid-phase peptide synthesis ensuring consistent quality and purity.
2.Certified Manufacturing: Fully compliant with ISO9001, GMP, HALAL, and COSMOS standards.
3.OEM/ODM Customization: Support for bulk orders, formulation design, and private label services.
4.Global Distribution: Expertise in international logistics, customs clearance, and export documentation.
5.Rigorous Testing: Every batch undergoes COA verification, ensuring purity, solubility, and microbiological safety.
Storage & Handling
1.Store in a tightly sealed container at <25°C, protected from moisture and direct light.
2.Reconstituted solutions should be stored at 4°C and used within a short period.
3.Shelf life: 24 months unopened.
Acetyl Tetrapeptide-5 is a next-generation cosmetic peptide that provides visible anti-aging benefits, particularly in the delicate eye area. By reducing puffiness, improving firmness, and restoring hydration balance, it delivers a youthful, refreshed appearance. Backed by scientific validation and certified production, our high-quality Acetyl Tetrapeptide-5 is ideal for B2B cosmetic manufacturers, formulators, and skincare brands seeking potent, multifunctional peptide ingredients for global markets.
Frequently Asked Questions (FAQ) – Acetyl Tetrapeptide-5 (Eyeseryl®)
1. What is Acetyl Tetrapeptide-5 (Eyeseryl®)?
Acetyl Tetrapeptide-5, also known as Eyeseryl®, is a bioactive peptide made of four amino acids. It is scientifically designed to target signs of skin aging such as puffiness, dark circles, and loss of elasticity, particularly in the delicate eye area.
2. How does Acetyl Tetrapeptide-5 work?
It works by improving lymphatic circulation, preventing glycation, and reducing fluid retention under the eyes. This leads to decreased puffiness, brighter skin, and improved firmness and elasticity.
3. What are the main benefits of using this peptide?
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Reduces under-eye puffiness and dark circles
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Enhances skin firmness and elasticity
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Provides moisturizing and anti-aging effects
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Ideal for sensitive and mature skin formulations
4. Is Acetyl Tetrapeptide-5 safe for all skin types?
Yes. It has high biocompatibility and is well-tolerated, making it suitable for sensitive, mature, and delicate skin areas, especially around the eyes.
5. How should Acetyl Tetrapeptide-5 be used in skincare formulations?
It is typically incorporated into serums, creams, and eye gels at concentrations ranging from 0.5% to 3%, depending on the desired effect. It should be added at the cool-down phase (below 40°C) to maintain peptide stability.
6. Can it be combined with other active ingredients?
Yes. Acetyl Tetrapeptide-5 is compatible with most common skincare actives, including hyaluronic acid, peptides, antioxidants, and plant extracts. Avoid extreme pH conditions (below 4 or above 8) to preserve efficacy.
7. How long does it take to see results?
Clinical studies suggest visible improvements in under-eye puffiness and skin elasticity can appear within 4 to 6 weeks of consistent use.
8. Is it tested clinically?
Yes. Acetyl Tetrapeptide-5 has been clinically studied for its anti-edema, anti-glycation, and anti-aging effects, showing measurable improvements in under-eye puffiness, skin brightness, and firmness.





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