Description

Product Name: Acetyl Hexapeptide-8 (Argireline)
CAS No.: 616204-22-9
Category: Cosmetic Peptide / Anti-Aging Active Ingredient
Molecular Formula: C₃₄H₆₀N₁₄O₁₂S
Molecular Weight: 888.0 Da
Molecular Weight Range: 850–900 Da
Appearance: White or off-white powder
Solubility: Soluble in water; compatible with most cosmetic bases
INCI Name: Acetyl Hexapeptide-8

Functions & Mechanism
1.Wrinkle Reduction:Inhibits the SNARE complex formation and catecholamine release, reducing repetitive muscle contractions that cause dynamic wrinkles, especially around eyes and forehead.
2.Anti-Aging & Firming:Stimulates collagen synthesis, enhances skin elasticity, and prevents sagging caused by loss of dermal structure.
3.Skin Smoothness & Hydration:Improves skin surface texture, softens lines, and enhances hydration synergy with hyaluronic acid.
4.Safe Neurotransmission Modulation:Provides visible wrinkle improvement without paralyzing facial muscles—gentle, non-toxic, and needle-free.
5.Clinical Efficacy:
1. 17% wrinkle depth reduction after 15 days (topical 10% solution).
2. 32% wrinkle reduction after 28 days of continuous use.
3.Noticeable smoothing and lifting effects validated by dermatological assessments.

Product Features
1.Clinically proven to visibly reduce expression lines.
2.Safe, non-toxic alternative to botulinum toxin injections.
3.High-purity peptide synthesized through solid-phase peptide technology.
4.Stable in aqueous and emulsion systems.
5.Ideal for daily anti-aging, firming, and rejuvenating skincare formulations.

Applications
1.Cosmetics:Anti-wrinkle creams, firming serums, eye contour products, anti-aging gels, lifting masks.
2.Personal Care:Daily moisturizing and rejuvenating skincare products for mature or stressed skin.
3.Professional Use:Formulations targeting fine lines and expression wrinkles around forehead, crow’s feet, and nasolabial folds.

Why Choose Us
1.Professional Manufacturer:
Decades of expertise in peptide synthesis and biological actives for cosmetics and pharmaceuticals.
2.Quality Certifications:
ISO 9001 / ISO 22000
GMP Certified Facility
Halal
Complies with EU REACH and FDA cosmetic ingredient standards
3.Customization & OEM/ODM Services:
Concentration adjustment, formula optimization, and bulk peptide production available.
4.Global Supply Chain:
Fast delivery with full export support including COA, MSDS, and formulation guide.
5.Sustainability Commitment:
Environmentally responsible synthesis using energy-efficient peptide coupling and minimal solvent waste.

Storage & Handling
1.Storage Conditions: Store in a cool, dry place, sealed tightly.
2.Recommended Temperature: 2–8°C
3.Shelf Life: 24 months (unopened)
4.Packaging: Available in 1g, 10g, 100g, and 1kg sterile containers.
5.Handling: Avoid repeated freeze-thaw cycles; reconstitute in sterile water or buffer before use.

Acetyl Hexapeptide-8 (Argireline) is a clinically validated, neuropeptide-mimicking cosmetic active known for its powerful wrinkle-smoothing and firming effects. Acting as a gentle, non-invasive alternative to Botox, it reduces muscle tension, minimizes fine lines, and restores youthful elasticity to the skin.

Produced under GMP and ISO-certified facilities, this high-purity peptide ensures consistent quality and safety for global skincare and cosmetic manufacturers. With proven efficacy, excellent stability, and a strong safety profile, Acetyl Hexapeptide-8 is the ideal choice for brands seeking premium anti-aging formulations that deliver visible, lasting results.

Frequently Asked Questions (FAQ) – Acetyl Hexapeptide-8 (Argireline)

1. What is Acetyl Hexapeptide-8?
Acetyl Hexapeptide-8, also known as Argireline, is a synthetic peptide composed of six amino acids. It mimics the N-terminal end of SNAP-25, a protein involved in facial muscle contraction, helping to reduce dynamic wrinkles and fine lines caused by repetitive facial expressions.

2. How does Acetyl Hexapeptide-8 work?
This peptide modulates neurotransmitter release at the neuromuscular junction, relaxing facial muscles. By reducing muscle movement, it decreases the appearance of expression lines and wrinkles, acting as a non-invasive alternative to Botox.

3. Is Acetyl Hexapeptide-8 safe for skincare use?
Yes. It is a widely studied cosmetic peptide with proven safety for topical use. Clinical studies have shown it reduces wrinkles without causing irritation or requiring injections.

4. What skin concerns does it target?
Acetyl Hexapeptide-8 is primarily used for anti-aging, targeting fine lines, crow’s feet, forehead wrinkles, and other dynamic wrinkles caused by facial expressions. It also helps improve skin elasticity and smoothness.

5. Can it replace Botox?
It is often called a “non-invasive alternative to Botox” because it relaxes facial muscles without injections. While it cannot completely replace Botox for deep wrinkles, it is effective for preventive and mild anti-aging treatments.

6. How should it be formulated in skincare products?
Acetyl Hexapeptide-8 is typically incorporated into serums, creams, masks, or lotions at concentrations supported by clinical research (usually 5–10%). It is water-soluble and compatible with most cosmetic formulations.

7. Are there any clinical studies supporting its efficacy?
Yes. Multiple studies published in the International Journal of Cosmetic Science and Dermatologic Therapy (2019–2024) confirm its ability to reduce wrinkle depth, improve skin elasticity, and relax facial tension.

8. How should it be stored?
Store in a cool, dry place away from direct sunlight. Proper storage ensures maximum peptide stability and efficacy in formulations.

9. Is it suitable for all skin types?
Yes. Acetyl Hexapeptide-8 is gentle and suitable for sensitive, normal, dry, and combination skin types.

10. What are the benefits for B2B cosmetic manufacturers?
It offers a high-demand, clinically validated anti-aging ingredient for premium skincare formulations. It enhances product performance, differentiates brands, and meets consumer demand for non-invasive wrinkle reduction solutions.